This article was originally published here
Too Med Infect Dis. 2022 Mar 25;7(4):53. doi: 10.3390/tropicalmed7040053.
Community transmission of SARS-CoV-2 in densely populated countries has been a concern since the start of the pandemic. Evidence for community transmission of SARS-CoV-2 based on population density gradient and socioeconomic status (SES) is limited. In June-September 2020, we conducted a descriptive longitudinal study to determine community transmission of SARS-CoV-2 in high and low density areas of Dhaka city. The secondary attack rate (SAR) was 10% in high density areas compared to 20% in low density areas. Individuals with high SES had a significantly higher level of SARS-CoV-2-specific anti-immunoglobulin G (IgG) antibodies on study day 1 (p = 0.01) and 28 (p = 0.03) compared to low SES people in high density areas. In contrast, levels of SARS-CoV-2-specific immunoglobulin M (IgM) seropositivity were comparable (p >0.05) in high and low SES individuals on Days 1 and 28 of the study in high and low density areas. Due to the similar household size, no difference in seropositivity rates along the population gradient was observed. However, high SES people showed higher seroconversion rates than low SES people. As no differences were observed based on population density, SES may play a role in SARS-CoV-2 transmission, an issue that requires further in-depth studies to better understand community transmission of SARS- CoV-2.